Technical Library

  1. Lovering, F.; Bikker, J.; Humblet, C. Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success. J. Med. Chem. 2009, 52 (21), 6752–6756.
  2. Tellis, J. C.; Kelly, C. B.; Primer, D. N.; Jouffroy, M.; Patel, N. R.; Molander, G. A. Single-Electron Transmetalation via Photoredox/Nickel Dual Catalysis: Unlocking a New Paradigm for Sp3–Sp2 Cross-Coupling. Acc. Chem. Res. 2016, 49 (7), 1429–1439.
  3. Jouffroy, M.; Primer, D. N.; Molander, G. A. Base-Free Photoredox/Nickel Dual-Catalytic Cross-Coupling of Ammonium Alkylsilicates. J. Am. Chem. Soc. 2016, 138 (2), 475–478.
  4. Chenneberg, L.; Lévêque, C.; Corcé, V.; Baralle, A.; Goddard, J.-P.; Ollivier, C.; Fensterbank, L. Single-Electron-Transfer Oxidation of Trifluoroborates and Silicates with Organic Reagents: A Comparative Study. Synlett 2016, 27 (05), 731–735.
  5. Patel, N. R.; Kelly, C. B.; Jouffroy, M.; Molander, G. A. Engaging Alkenyl Halides with Alkylsilicates via Photoredox Dual Catalysis. Org. Lett. 2016, 18 (4), 764–767.
  6. Raynor, K. D.; May, G. D.; Bandarage, U. K.; Boyd, M. J. Generation of Diversity Sets with High Sp3 Fraction Using the Photoredox Coupling of Organotrifluoroborates and Organosilicates with Heteroaryl/Aryl Bromides in Continuous Flow. J. Org. Chem. 2018, 83 (3), 1551–1557.
  7. Patel, N. R.; Molander, G. A. Phenol Derivatives as Coupling Partners with Alkylsilicates in Photoredox/Nickel Dual Catalysis. J. Org. Chem. 2016, 81 (16), 7271–7275.
  8. Lévêque, C.; Chenneberg, L.; Corcé, V.; Ollivier, C.; Fensterbank, L. Organic Photoredox Catalysis for the Oxidation of Silicates: Applications in Radical Synthesis and Dual Catalysis. Chem. Commun. 2016, 52 (64), 9877–9880.
  9. Vara, B. A.; Jouffroy, M.; Molander, G. A. C(Sp3)–C(Sp2) Cross-Coupling of Alkylsilicates with Borylated Aryl Bromides – an Iterative Platform to Alkylated Aryl- and Heteroaryl Boronates. Chem. Sci. 2017, 8 (1), 530–535.
  10. Lin, K.; Wiles, R. J.; Kelly, C. B.; Davies, G. H. M.; Molander, G. A. Haloselective Cross-Coupling via Ni/Photoredox Dual Catalysis. ACS Catal. 2017, 7 (8), 5129–5133.
  11. Matsui, J. K.; Lang, S. B.; Heitz, D. R.; Molander, G. A. Photoredox-Mediated Routes to Radicals: The Value of Catalytic Radical Generation in Synthetic Methods Development. ACS Catal. 2017, 7 (4), 2563–2575.
  12. Patel, N. R.; Kelly, C. B.; Siegenfeld, A. P.; Molander, G. A. Mild, Redox-Neutral Alkylation of Imines Enabled by an Organic Photocatalyst. ACS Catal. 2017, 7 (3), 1766–1770.
  13. Zheng, S.; Primer, D. N.; Molander, G. A. Nickel/Photoredox-Catalyzed Amidation via Alkylsilicates and Isocyanates. ACS Catal. 2017, 7 (11), 7957–7961.
  14. Jouffroy, M.; Kelly, C. B.; Molander, G. A. Thioetherification via Photoredox/Nickel Dual Catalysis. Org. Lett. 2016, 18 (4), 876–879.
  15. Phelan, J. P.; Lang, S. B.; Compton, J. S.; Kelly, C. B.; Dykstra, R.; Gutierrez, O.; Molander, G. A. Redox-Neutral Photocatalytic Cyclopropanation via Radical/Polar Crossover. J. Am. Chem. Soc. 2018, 140 (25), 8037–8047.
  16. Bezençon, O.; Heidmann, B.; Siegrist, R.; Stamm, S.; Richard, S.; Pozzi, D.; Corminboeuf, O.; Roch, C.; Kessler, M.; Ertel, E. A.; et al. Discovery of a Potent, Selective T-Type Calcium Channel Blocker as a Drug Candidate for the Treatment of Generalized Epilepsies. J. Med. Chem. 2017, 60 (23), 9769–9789.