| Thermoset | Structure | Silane Functionality | Suggestions for Primary Screening |
|---|---|---|---|
| Acrylate, UV cure |  | Acrylate Vinyl/Olefin | SIA0200.0, SIM6487.4 SIS6994.0 |
| Diallylphthalate |  | Amine Vinyl/Olefin Dipodal | SIA0591.0, SIA0610.0 SIS6994.0 SIB1824.5 |
| Epoxy |  | Amine Anhydride Epoxy Dipodal | SIA0591.0, SIT8398.0 SIT8192.6 SIG5840.0 SIB1834.0 |
| Epoxy, UV Cure |  | Amine Epoxy | SIA0591.0, SIT8398.0 SIE4668.0, SIE4670.0 |
| Polyimide |  | Amine Halogen Dipodal | SIA0599.2, SIA0591.0 SIC2295.5, SIC2296.2 SIB1833.0 |
| Furan |  | Amine Epoxy | SIA0611.0, SIA0599.0 SIG5840.0 |
| Melamine |  | Amine Hydroxyl Dipodal | SIA0611.0, SIA0599.0 SIB1140.0 SIB1833.0, SIT8717.0 |
| Parylene |  | Halogen Vinyl/Olefin Dipodal | SIC2295.5 SIS6990.0, SIM6487.4 SIB1832.0, VMM-010 |
| Phenol-formaldehyde |  | Amine Epoxy | SIA0611.0, SIT8187.5 SIE4670.0, SIG5840.0 |
| Methylmethacrylate, cast |  | Acrylate Amine | SIM6487.4, SIA0200.0 SIB1828.0 |
| Polyester, unsaturated |  | Acrylate Vinyl/Olefin | SIM6487.4 SIS6994.0, SIV9112.0 |
| Urea-formaldehyde |  | Amine Hydroxyl | SIA0610.0, SIU9055.0 SIB1140.0 |
| Urethane |  | Amine Isocyanate Sulfur | SIA0610.0, SIM6500.0 SII6455.0 SIM6476.0 |
| Thermoplastic | Structure | Silane Functionality | Suggestions for Primary Screening |
|---|---|---|---|
| Polyacetal |  | Vinyl/Olefin | SIS6994.0 |
| Polyacrylate |  | Amine | SIU9058.0, SIA0610.0 |
| Polyamide |  | Amine Dipodal Water-borne | SIA0610.0, SIA0614.0 SIB1834.1, SSP-060 WSA-7011 |
| Polyamide-imide |  | Amine Halogen | SIA0610.0 SIC2295.5 |
| Polybutylene terephthalate |  | Amine Isocyanate | SIA0610.0 SII6455.0 |
| Polycarbonate |  | Amine | SIA0591.0, SIA0610.0 |
| Polyether ketone |  | Amine Dipodal | SIA0591.0 SIT8717.0 |
| Polyethylene |  | Amine Vinyl/Olefin | SIA0591.0, SIT8398.0 SSP-055, SIV9112.0 |
| Polyphenylene sulfide |  | Amine Halogen Sulfur | SIA0605.0 SIC2295.5 SIM6476.0 |
| Polypropylene |  | Acrylate Azide Vinyl/Olefin | SIM6487.4 SIA0780.0 VEE-005, SSP-055 |
| Polystyrene |  | Acrylate Dipodal | SIM6487.4 SIB1831.0 |
| Polysulfone |  | Amine | SIA0591.0, SIU9055.0 |
| Polyvinyl butyral |  | Amine | SIA0611.0, SIU9058.0 |
| Polyvinyl chloride |  | Amine Sulfur | SIA0605.0 SIM6474.0, SIB1825.0 |
| Sealant/Elastomer | Structure | Silane Functionality | Suggestions for Primary Screening |
|---|---|---|---|
| Acrylic latex |  | Acrylate Vinyl/Olefin Water-borne | SIM6487.4 SIV9210.0 WSA-7021, WSAV-6511 |
| Butyl |  | Acrylate Sulfur Vinyl/Olefin | SIM6487.4 SIB1825.0, SIM6476.0 SSP-055, VEE-005 |
| Epichlorohydrin |  | Amine Sulfur | SIA0605.0 SIM6474.0 |
| Fluorocarbon |  | Amine Dipodal | SIB1834.1 SIT8717.0 |
| Isoprene |  | Sulfur Vinyl/Olefin | SIM6474.0, SIM6476.0 SSP-055, VEE-005 |
| Neoprene |  | Sulfur Vinyl/Olefin | SIM6474.0, SIM6476.0 SSP-055, VEE-005 |
| Nitrile |  | Epoxy Sulfur | SIG5840.0 SIB1825.0 |
| Polysulfide |  | Epoxy Sulfur | SIG5840.0 SIB1825.0, SIM6476.0 |
| SBR |  | Amine Sulfur | SIA0605.0 SIB1825.0, SIM6486.0 |
| Silicone (hydroxyl-terminated) |  | Amine Vinyl/Olefin Dipodal | SIA0605.0, SIA0589.0 SIV9098.0, VMM-010 SIB1824.0 |
| Silicone (vinyl-terminated) |  | Acrylate Vinyl/Olefin | SIM6487.4 SIA0540.0, VMM-010 |
| Biomaterial | Site/Type | Silane Functionality | Co-reactant | Suggestions for Primary Screening | References |
|---|---|---|---|---|---|
| Oligonucleotides | Hydroxyl Diamine Semicarbazide | Cobalt ethylenediamine | SIB1140.0 SIA0591.0 SIS6944.0 | G. McGall et al, J. Am. Chem. Soc., 119, 5081, 1997. F. Chow, in “Silylated Surfaces” D. Leyden ed., Gordon & Breach, 1978, p.301. M. Podyminogin et al, Nucleic Acid Res., 2001, 29, 5090. |
|
| DNA | Terminal-Favored Pendant Amine Pendant Amine Pendant Amine | Vinyl/Olefin Aldehyde Diamine Epoxy | SIO6708.0, SIU9049.0 SIT8194.0 SIA0594.0, SID3543.0 SIE4675.0, SIG5838.0 | A. Bensimon, Science, 265, 2096, 1994. J. Grobe et al, J. Chem. Soc. Chem. Commun, 2323, 1995. C. Kneuer et al, Int’l J. Pharmaceutics, 196(2), 257, 2000. |
|
| Protein | Lysine Lysine Lysine Cysteine Tyrosine Heparinated Immunoglobin Antibody | Aldehyde Amine Amine Sulfur Nitrobenzamide Amine/Quat Pyridyl-thio Cyano | Glutaraldehyde Thiophosgene Dithionite NaNO2/HCl | SIT8194.0 SIA0611.0, SIA0595.0 SIA0611.0 SIM6476.0 SIT8191.0, SIA0599.0 SSP-060, SIT8415.0 SIP6926.4 SIC2456.0 | J. Grobe et al, J. Chem. Soc. Chem. Commun, 2323, 1995. H. Weetall, US Pat. 3,652,761. G. Royer, CHEMTECH, 4, 699, 1974. S. Bhatia et al, Anal. Biochem., 178, 408, 1989. J. Venter et al, Proc. Nat. Acad. Soc., 69(5), 1141, 1972. R. Merker et al, Proc. Artificial Heart Prog. Conf., June 9-13, 1969 HEWNIH, p29. S. Falipou, Fundamental & Applied Aspects of Chemically Modified Surfaces, p389, 1999. |
| Cell-Organelle | Chloroplast Mitochondria | Alkyl Alkyl | SIO6645.0 SIO6645.0 | B. Arkles et al, in “Silylated Surfaces” D. Leyden ed., Gordon & Breach, 1978, p363. B. Arkles et al, J. Biol. Chem., 250, 8856, 1975. |
|
| Whole Cell | Erythrocytes | Short Alkyl | SIE4901.4 | B. Arkles et al, in “Silylated Surfaces” D. Leyden ed., Gordon & Breach, 1978, p363. | |
| Whole Cell (causing lysis) | Procaryotic | Alkyl-quat | SIO6620.0, SID3392.0 | W. White et al in “Silanes, Surfaces & Interfaces” ed. D. Leyden, Gordon & Breach, 1986, p. 107. | |
| Tissue | Histological samples | SIA0611.0, SIA0610.0 |